About The Event

Over the past decade, modern genomics and transcriptomics have discovered a wealth of hidden small genes containing short open reading frames (sORFs) in many prokaryotic genomes. These sORFs encoding small proteins of <50 amino acids in length are typically missed by automated gene predictions. Recent efforts focusing on their functions have discovered small proteins impacting disparate cellular processes, running the gamut of energy generation, transport, virulence, symbiosis, sporulation, and photosynthesis.

Besides, new emerging technologies (e.g. riboprofiling, new proteomics/peptidomics techniques) now enable profiling and systematic investigation on physiological roles of small protreins.

This conference in the frame of the priority program SPP2002 “Small Proteins in Prokaryotes, an Unexplored World” aims at showcasing small proteins in Prokaryotes from different angles: in method development for detection and analysis as well as investigating physiological roles of small proteins in diverse bacteria and archaea. This meeting will bring together researchers at all career stages with the goals of sharing new insights, establishing collaborations and cross-fertilization of ideas.

We look forward to welcoming you to the Harnack-Haus in Berlin in October 2023.


Harnack-Haus in Berlin


4.- 6. October, 2023


Speakers from Europe

Tracy Palmer (Newcastle University, UK)
Frank Sobott (University of Leeds, UK)
Roman Sobotka (The Czech Academy of Sciences, CZ)
Monika Fuxreiter (University of Padova, IT)

Speakers from outside Europe

Joseph Wade (National Institutes of Health, US)
Gisela Storz (National Institutes of Health, US)
Kumaran Ramamurthi (National Institutes of Health, US)
Elisabeth Fozo (University of Tennessee, US)


The program is currently still in the planning stage.

„Please note that the times correspond to the CEST.“

Sunday - September 19th
18:00-18:15 Ruth Schmitz-Streit  Welcome by SPP2002 speaker
18:15-19:30 Gisela Storz Small, regulatory proteins expressed from INTRAgenic sequences
Monday - September 20th
9:00 – 9:35 Sandra Maaß (Becher lab) and Andreas Tholey Z1: Proteomics and peptidomics for the identification and functional characterization of sORF encoded proteins
9:35 – 9:55 Lydia Hadjeras (Sharma lab) Z2: Mapping prokaryotic translatomes with ribosome profiling and its derivative approaches
9.55 – 10:15 Rick Gelhausen (Backofen lab) Bioinformatics of Ribosome profiling: The next chapter
10:15 – 10:35 Rotem Sorek Small proteins that direct communication in phages and bacteria
10:35 – 10:50 Refreshments
10:50 – 11:10 Franz Narberhaus The elusive function of small DUF1127 proteins
11:10 – 11:30 Jessica Grube (Engelmann lab) N-terminomic analysis in Staphylococcus aureus enables identification of misannotated N-termini and proteoforms
11:30 – 11:50 Bork Berghoff Type I toxin-dependent persister formation in Escherichia coli
11:50 – 12:10 Deniz Üresin (Soppa lab) Important roles of zinc finger µ-proteins in Haloferax volcanii.
12:10 – 12:30 Tim Habenicht (Schmitz-Streit lab) Small proteins involved in nitrogen metabolism in Methanosarcina mazei
12:30 – 13:30 Lunch
13:30 – 14:05 Monika Fuxreiter Versatile interaction behaviors of proteins in complexes and condensates
14:05 – 14:40 Reinhard Sterner Analysis of allosteric communication in a multi-enzyme complex by ancestral sequence reconstruction
14:40 – 15:00 Dennis Pyper (Schwalbe lab) How we use NMR spectroscopy to determine the structure and dynamics of small proteins
15:00 – 15:15 Refreshments
15:15 – 15:50 Kumaran Ramamurthi SpoVM: a small protein that builds a mighty structure
15:50 – 16:25 Frank Sobott Mass spectrometry approaches to dynamic protein structure: from disordered peptides to membrane pores
16:25 – 16:45 Jing Yuan A small membrane protein that inhibits the virulence regulator PhoQ
16:45 – 17:05 Kavyaa Venkat (Papenfort lab) A dual-function RNA balancing carbon uptake and central metabolism in Vibrio cholerae
Tuesday - September 21st
11:00 - 11:35 Johanna Bosch (Clavel lab) and Qingyin Pu (Gulder lab) Ecology and functions of small SCIFF proteins in the gut microbiome
11:35 – 11:55 Jakob Meier-Credo (Langer lab) Small protein discovery in Pseudomonas stutzeri using combined bottom-up and top-down proteomics and proteogenomics
11:55 – 12:15 Hans-George Koch Small membrane proteins in bacteria: exploring their membrane insertion and function
12:15 – 12:50 Ben Luisi  The small transmembrane protein AcrZ and its role in bacterial drug efflux
12:50 – 13:50 Lunch
13:50 – 14:10 Luna Alvarenga-Lucius (Hagemann lab) Is the small protein HliR1 participating in photosystem I (super)complex formation in Synechocystis?
14:10 – 14:30 Vanessa Krauspe (Hess lab) Analysis and characterization of small proteins and their function in the cyanobacterium Synechocystis sp. PCC 6803
14:30 – 14:50 Marc Nowaczyk Small proteins in cyanobacterial membrane protein complexes
14:50 – 15:25 Roman Sobotka Photoprotection of photosynthesis by (small and green) High-light inducible proteins
15:25 – 15:40 Refreshments
15:40 – 16:15 Elizabeth Fozo This conference in the frame of the priority program SPP2002 “Small Proteins in Prokaryotes, an Unexplored World” aims at showcasing small proteins in Prokaryotes from different angles
16:15 – 16:50 Joseph Wade Pervasive translation of short ORFs in Mycobacterium tuberculosis
16:50 – 17:10 Ileana Salto (Dersch lab) Identification and characterization of small proteins implicated in Yersinia virulence and physiology
17:10 – 17:30 Elisa Venturini (Vogel lab) A global data-driven census of Salmonella small proteins and their potential functions in bacterial virulence
17:30 – 18:05 Branislav Lilic (Bläsi lab) Pseudomonas aeruginosa
18:05 – 18:25 Kathrin Froschauer (Sharma lab) Exploring small proteins in the food-borne pathogen Campylobacter jejuni
18:25 Ruth Schmitz-Streit Closing Remarks

Abstract Submission

Structure the abstract as follows:

  • Titel 
  • Authors: (underlining presenting authors)
  • Affiliation
  • Abstract: (max. 300 Words)
  • References: (3 maximum)

Submit your abstract by July 31st.
For submission please send it to fpetersen@ifam.uni-kiel.de.
From August 18th you will receive feedback on the abstract.

Career Workshop

SPP2002 Talent Management Workshop

It is our goal to continuously work on the professional qualification of our young scientists for which we offer a talent management workshop especially for PhD students in the course of this conference

In the frame of this workshop we will start with Professional Networking in Module 1 (including exercises, theory and practical tips) and will focus on the ability and necessity to give constructive feedback in Module 2. Moreover does the implementation of the workshop in our conference offer a good opportunity to apply and deepen what has been learned and exchange content and experiences between the participants during the duration of the event.

Ute E. Jülly, our “Talent Management”- Coach, will be around for further spontaneous interactions.

The workshop will be integrated into the conference and will take place in person in Berlin for all SPP2002 members.

Our Coach, Ute E. Jülly, earned her Masters Degree in Intercultural Communication/Anthropology and Romance Languages, Freiburg University, Germany. With more than 25 years of experience and research Ute E. Jülly is a specialist for International Scientific Personal Development. In her book “Haptik wirkt”, i.e.: “The relevance of haptics” she developed a brand new method in coaching and consulting. Since 2018 Ute strengthens the SPP 2002. For more information please visit her website:


We'd love to hear from you

Contact Us

Questions about the SPP2002 Small Protein Meeting?


List of Hotels

Harnack-Haus Berlin
Ihnestr. 16 – 20, 14195 Berlin
Tel: +49(30) 84 13 38 00
“booking code: 7558”


Seminaris Campus Hotel Berlin
Takustrasse 39 | 14195 Berlin | Germany
Tel: +49 30 557 797 420

Hotel Steglitz International
Schlossstraße/Albrechtstraße 2
12165 Berlin
Tel: +49(0)30-790050

Hotel Pension Dahlem
Unter den Eichen 89a, 12205 Berlin
Tel:+49 (0) 30 – 83 11 050

Hotel Landhaus Schlachtensee
Bogotastr. 9, D-14163 Berlin
Tel.: +49-30-80 99 47-0

enjoy hotel Berlin City Messe
Rudolstädter Straße 42
10713 Berlin
Tel. +49 030 897830